Reply To: Gout Seeker Archive

Keith Taylor

Sounds encouraging, Malcolm.

On colchicine, it’s good to know how it works. Our immune system fights uric acid crystals. When overwhelmed, immune system cells send out signals for reinforcements. Essentially, white blood cells grow and divide, so our army is bigger. And, this is what produces painful inflammation. Colchicine slows the cell division process. But, it does nothing for existing inflammation.

It’s best as a preventative. Or, at the first hint of a gout flare. It is useful after that, to slow spreading inflammation. But, once a gout attack has started, you should support colchicine with an NSAID. Ibuprofen and naproxen are the most common these days. But, your doctor or pharmacist can advise on different anti-inflammatories to suit your medical history. In extreme cases, you also need a painblocker such as paracetamol/acetaminophen. Again, medical professionals will advise on safe, compatible combinations.