Stopping Gout Together › Forums › Help My Gout! The Gout Forum › Allopurinol makes me drowsy. Should I take it at night? › Reply To: Allopurinol makes me drowsy. Should I take it at night?
I have taken Allopurinol every day for over 18 months and I’ve never felt tired, groggy, or not alert. With most medications, the drug producers have to disclose every POTENTIAL side effect, and more often than not, drowsiness comes up quite often. Allopurinol also may cause upset stomach, and other GI problems, but I haven’t had any of those either.
I take my dose in the morning simply because it’s easier for me to remember to do so. Like Keith says, it really doesn’t matter when you take it because of the long acting period in the body.