Reply To: First posting in Personal Gout Diary

Steve Krause

After five and half weeks on 100mg of allopurinol per day I went and got lab tests. My UA dropped from above 9.1 down to 5.5. My ALT level actually got better, down from 29 to 19. My Creatinine lowered from 1.25 to 1.19 which is in the normal range. So I appear to be tolerating the allopurinol this time.

I have not had any dramatic gout attack during the last five weeks. My ankles and feet have felt sore and stiff at times but not hot or swollen. One wrist hurt but might have been a pulled tendon or ligament from lifting something heavy and that went away in a couple days. The rheumatologist has prescribed Sulindac (two per day), an NSAID that he says might be easier than ibuprofen on the kidneys, to be taken as needed if I need pain relief. I have taken them when my feet felt kind of stiff. I don’t know if the stiffness is from the gout but taking the Sulindac is effective for that. I’ve taken one at a time about 3 a week.

The doctor has said that getting the UA level under 6 is good and to continue with the 100mg and test in four months. I am going to do that. Anybody have any predictions whether the allopurinol will continue to lower the levels? It would be great if it really brought the levels lower over more time at that dosage, as my liver and kidneys have so far tolerated that level.