Stopping Gout Together › Forums › Help My Gout! The Gout Forum › Can I start allupurinol during an attack? › Reply To: Can I start allupurinol during an attack?

Yes, John.
Start Allopurinol Quickly, But Carefully.
Quickly – the sooner you start, the sooner you gain complete gout recovery.
Carefully – note that the people in that study took indomethacin to support colchicine. Because colchicine limits new inflammation. But does nothing to reduce existing inflammation. So, ask your doctor/pharmacist about Indocin. Or other anti-inflammatory such as ibuprofen, naproxen or diclofenac. Also, you could ask about taking acetaminophen at the same time to block any residual pain (if necessary). There are lots of possible colchicine combinations, as you can see from those discussions.

How much time will you waste by delaying start of allopurinol therapy?