Reply To: Are Gall Bladder Removal and Gout Related?

Stopping Gout Together Forums Help My Gout! The Gout Forum Are Gall Bladder Removal and Gout Related? Reply To: Are Gall Bladder Removal and Gout Related?

#7802
Keith Taylor
Keymaster


That “Bile and Uric Acid” report is very interesting to me. So thank you to the anonymous reader who supplied the information. Unfortunately, the link doesn’t work. But the report is easy to find (http://www.jbc.org/content/292/52/21397). Also, it’s my first candidate for a new way to share gout research information. So keep watching the email updates!
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I’m guessing that the logical link to the main question in this topic is:
Bile salts limit xanthine oxidase activity. Therefore after gallbladder removal, this natural alternative to allopurinol is no longer available. So gout occurs?

Anyway, that’s my current working hypothesis. But I still can’t find good data linking urate levels before and after cholecystectomy. So this is still a topic that creates more questions than answers.