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Why colchicine with Allopurinol and Indomethacin?

Stopping Gout Together Forums Help My Gout! The Gout Forum Why colchicine with Allopurinol and Indomethacin?

This topic contains 4 replies, has 4 voices, and was last updated by  Keith Taylor 1 year, 1 month ago.

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  • #4907

    Eric Bolvin
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    Hi; Recently had a gout attack and treated it with Indocin, colchicine, and allopurinol. Am now taking just allopurinol and doing fine. Uric acid is controlled.
    Stopped taking colchicine because it wasn’t insured, but am getting some from Canada.
    So when should I take colchicine? I know to take Indocin for acute attacks, but what about colchicine?

  • #4908

    d q
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    Colchicine is used for both prophylaxis treatment(preventative) and as an acute attack treatment when you feel a gout attack coming.

    Generally speaking, it is administered when starting new uric acid controlling medication such as allopurinol or febuxostat AND when increasing your dose of allopurinol or febuxostat (if required) to prevent attacks whilst those medications begin working and dissolving uric acid crystals or tophi.

    It is also taken on the first feeling that a gout attack is about to begin to stop the spread of inflammation and to minimize the length of the attack.

    The dosages should be set by your rheumatologist when prescribing it to you. There are generic dosages that you can use but I would recommend you don’t follow them as colchicine can be toxic if administered incorrectly

    Take a look at Acute Gout Attack Treatment Plan for a little information.

    It is best to seek rheumatologist advice before taking any colchicine.

  • #4911

    nobody
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    Other situations in which you might want to take colchicine while you know you could experience an attack at any time:
    Say you’re planning a business trip and you realize that an attack right before or during that trip would be extremely inconvenient. Take colchicine a few days before and during the trip.
    Say you’re planning to do something which has triggered attacks before such as a bit of trekking. Take colchicine from the day before to the day after.
    You get the idea. Just because you don’t need a prophylactic every day doesn’t mean you never need it.

    You might also use colchicine if you are afflicted with a persistent attack which indo can’t seem to quell fully or a seemingly unending series of short attacks.

  • #4913

    Eric Bolvin
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    Thanks all!

  • #4927

    Keith Taylor
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    GoutPal Scholar Badge Rank: Scholar

    Hi Eric,

    Am now taking just allopurinol and doing fine. Uric acid is controlled.

    If that’s true, you don’t need colchicine. But is your uric acid below 6mg/dL (better below 5)? Because 6 is the maximum safe level, and 5 gives a good safety margin.

    Finally, if you’ve only just got down to that level, you might still get occasional flares until more old uric acid crystals dissolve. But if Indocin is working OK for you, there’s no need for colchicine.


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